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Found 45 with Last Name = 'hockerman' and Initial = 'gh'
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007119(4-Amino-3-phenyl-butyric acid | CHEMBL53073)
Affinity DataKi:  9.20E+4nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007119(4-Amino-3-phenyl-butyric acid | CHEMBL53073)
Affinity DataKi:  1.77E+5nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007118(4-Amino-3-(5-chloro-thiophen-2-yl)-butyric acid | ...)
Affinity DataIC50:  610nMAssay Description:Binding affinity to GABA-B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427602(CHEMBL2322937)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)
Affinity DataEC50:  3.78E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)
Affinity DataEC50:  3.78E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427604(CHEMBL2322936)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427605(CHEMBL2322932)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427606(CHEMBL2322945)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427607(CHEMBL2322944)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427608(CHEMBL2322943)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427609(CHEMBL2322941)
Affinity DataEC50:  9.93E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427610(CHEMBL2322940)
Affinity DataEC50:  6.69E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427611(CHEMBL2322939)
Affinity DataEC50:  6.18E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427612(CHEMBL2322942)
Affinity DataEC50:  5.35E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427613(CHEMBL2322935)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462450(CHEMBL4238712)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427614(CHEMBL2322946)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462442(CHEMBL4245403)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50427613(CHEMBL2322935)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462443(CHEMBL4238315)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462444(CHEMBL4244129)
Affinity DataEC50:  9.10E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50427613(CHEMBL2322935)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462445(CHEMBL4246158)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462444(CHEMBL4244129)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462446(CHEMBL4238634)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462447(CHEMBL4248377)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462448(CHEMBL4241188)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462449(CHEMBL4247210)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462450(CHEMBL4238712)
Affinity DataEC50:  3.27E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462451(CHEMBL4249205)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462452(CHEMBL4244940)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462453(CHEMBL4244933)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462446(CHEMBL4238634)
Affinity DataEC50:  1.94E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462454(CHEMBL4250786)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50462443(CHEMBL4238315)
Affinity DataEC50:  5.74E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427601(CHEMBL2322938)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108998(CHEMBL3600560)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human recombinant GABA-B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108997(CGP-71872 | CHEMBL1628548)
Affinity DataKd:  1nMAssay Description:Binding affinity to GABA-B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108996(CGP-7930 | CHEMBL1256697)
Affinity DataEC50:  5.37E+3nMAssay Description:Positive allosteric modulator activity at GABA-B receptor (unknown origin) assessed as potentiation of 1 uM GABA-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)
Affinity DataEC50:  1.59E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed