Affinity DataKi: 0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00530nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.00530nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.00570nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00650nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.00650nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.00790nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00790nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00900nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0160nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0340nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Displacement of [3H]-substance P from rat NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0460nM ΔG°: -59.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataKi: 0.0750nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0750nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0770nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0820nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0840nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0890nMAssay Description:Displacement of [3H]substance P from rat NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataKi: 0.0970nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H] DAMGO from rat mu-opioid receptorMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 0.112nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in human/mouse HN9.10 cell membranes after 3 hrs by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding a...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of Eu-DTPA-PEGO-NDP-alpha-MSH-NH2 from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membranesMore data for this Ligand-Target Pair