Compile Data Set for Download or QSAR
maximum 50k data
Found 163 with Last Name = 'james' and Initial = 'if'
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataKi:  0.120nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataKi:  0.120nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052327(6-hydroxy-15-isopropenyl-4,13,17-trimethyl-5-oxo-(...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052320(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  1nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052323((4-Hydroxy-3-methoxy-phenyl)-acetic acid 4a,7b-dih...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052333(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052328(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052330(13-benzyl-5,6-dihydroxy-15-isopropenyl-4,17-dimeth...)
Affinity DataKi:  11nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052321(CHEMBL98634 | Phenyl-acetic acid (1aR,1bS,4aR,7aS,...)
Affinity DataKi:  600nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM20461((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50052324(13-benzyl-6-hydroxy-8-hydroxymethyl-15-isopropenyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  22nMAssay Description:Inhibition of rat CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218121(CHEMBL390675 | naphthalen-1-yl-(4-pentylaminonapht...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218123(CHEMBL244402 | naphthalen-1-yl-(4-butoxynaphthalen...)
Affinity DataIC50:  48nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218123(CHEMBL244402 | naphthalen-1-yl-(4-butoxynaphthalen...)
Affinity DataIC50:  85nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218120(CHEMBL243334 | naphthalen-1-yl-(4-propoxynaphthale...)
Affinity DataIC50:  90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  98nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218121(CHEMBL390675 | naphthalen-1-yl-(4-pentylaminonapht...)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218119((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Affinity DataIC50:  160nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199822(2-(4-(4-bromophenyl)pyridin-3-yl)-3-sec-butylthiaz...)
Affinity DataIC50:  210nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218120(CHEMBL243334 | naphthalen-1-yl-(4-propoxynaphthale...)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199819(3-isobutyl-2-(4-p-tolylpyridin-3-yl)thiazolidin-4-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199841(2-(3-(4-bromophenyl)pyridin-4-yl)-3-isobutylthiazo...)
Affinity DataIC50:  500nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199832(3-isobutyl-2-(4-(4-vinylphenyl)pyridin-3-yl)thiazo...)
Affinity DataIC50:  510nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199825(3-isobutyl-2-(3-(4-vinylphenyl)pyridin-4-yl)thiazo...)
Affinity DataIC50:  530nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199846(3-cyclopentyl-2-(2-(4-(trifluoromethyl)phenyl)pyri...)
Affinity DataIC50:  560nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199831(2-(3-(4-chlorophenyl)pyridin-4-yl)-3-isobutylthiaz...)
Affinity DataIC50:  580nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199837(3-isobutyl-2-(3-p-tolylpyridin-4-yl)thiazolidin-4-...)
Affinity DataIC50:  590nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199827(2-(4-(4-chlorophenyl)pyridin-3-yl)-3-isobutylthiaz...)
Affinity DataIC50:  600nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199818(2-(4-(4-bromophenyl)pyridin-3-yl)-3-cyclopentylthi...)
Affinity DataIC50:  630nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199812(2-(4-(4-bromophenyl)pyridin-3-yl)-3-isobutylthiazo...)
Affinity DataIC50:  660nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218119((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Affinity DataIC50:  660nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199840(2-(2-(4-bromophenyl)pyridin-3-yl)-3-isobutylthiazo...)
Affinity DataIC50:  700nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199826((R)-3-isobutyl-2-(4-p-tolylpyridin-3-yl)thiazolidi...)
Affinity DataIC50:  730nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199826((R)-3-isobutyl-2-(4-p-tolylpyridin-3-yl)thiazolidi...)
Affinity DataIC50:  730nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199820((R)-3-isobutyl-2-(4-(4-(trifluoromethyl)phenyl)pyr...)
Affinity DataIC50:  770nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199820((R)-3-isobutyl-2-(4-(4-(trifluoromethyl)phenyl)pyr...)
Affinity DataIC50:  770nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199839(2-(4-(4-ethylphenyl)pyridin-3-yl)-3-isobutylthiazo...)
Affinity DataIC50:  880nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218122(CHEMBL244607 | naphthalen-1-yl-(4-phenethyloxynaph...)
Affinity DataIC50:  930nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199817(3-isobutyl-2-(4-(4-(trifluoromethyl)phenyl)pyridin...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218118(CHEMBL244189 | [4-(2-morpholin-4-ylethoxy)naphthal...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199811(2-(2-(4-chlorophenyl)pyridin-3-yl)-3-isobutylthiaz...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199836(2-(4-(4-fluorophenyl)pyridin-3-yl)-3-isobutylthiaz...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199830(CHEMBL234510 | N-isobutyl-4-oxo-3-(2-(pyridin-2-yl...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199845(2-(4-(4-bromophenyl)pyridin-3-yl)-3-cyclopropylthi...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 163 total ) | Next | Last >>
Jump to: