Found 16 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50366620' TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H]RTX from Vanilloid receptor in Rat spinal cord membranesMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 0.0230nMAssay Description:In vitro binding affinity towards vanilloid receptor by [3H]RTX displacement.More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 0.0426nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 0.0430nMAssay Description:Displacement of [3H]RTX from rat TRV1 expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Binding affinity against Vanilloid receptor in dorsal Root Ganglion (DRG) membranes using [3H]RTX binding assay.More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptakeMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at rat TRPV1 expressed in CHO cells assessed as 45Ca2+ uptakeMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as stimulation of Ca2+ uptakeMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 0.0190nMAssay Description:Agonist activity at human recombinant TRPV1 expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 0.0190nMAssay Description:Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
