Compile Data Set for Download or QSAR
maximum 50k data
Found 1486 with Last Name = 'jenkins' and Initial = 'j'
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203905(4-(4-benzoylamino-naphthalene-1-sulfonylamino)-pip...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078161(CHEMBL3417702)
Affinity DataKi:  0.200nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078159(CHEMBL3417700)
Affinity DataKi:  0.240nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203831(CHEMBL374939 | N-(4-{[(1-butyrylpiperidin-4-yl)ami...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078162(CHEMBL3417703)
Affinity DataKi:  0.310nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi:  0.430nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078163(CHEMBL3417704)
Affinity DataKi:  0.450nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078164(CHEMBL3417705)
Affinity DataKi:  0.480nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203834(2-methyl-N-{4-[({1-[(2S)-pyrrolidin-2-ylcarbonyl]p...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203834(2-methyl-N-{4-[({1-[(2S)-pyrrolidin-2-ylcarbonyl]p...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203832(4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfony...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203919(2-methyl-N-[4-({[1-(pyrrolidin-1-ylcarbonyl)piperi...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi:  1.5nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203914(CHEMBL375854 | N-[4-({[1-(azetidin-3-ylcarbonyl)pi...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203920(CHEMBL221867 | N-{4-[1-(4-amino-butyryl)-piperidin...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203881(4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfony...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203871(4-({[4-(benzoylamino)-1-naphthyl]sulfonyl}amino)-N...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078165(CHEMBL3417706)
Affinity DataKi:  1.80nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078158(CHEMBL3417699)
Affinity DataKi:  2nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203859(4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfony...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203857(CHEMBL218037 | ethyl 4-({[5-(benzoylamino)-1-napht...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078157(CHEMBL3417698)
Affinity DataKi:  2.30nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203900(2-methyl-N-[4-(1-propionyl-piperidin-4-ylsulfamoyl...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078159(CHEMBL3417700)
Affinity DataKi:  2.70nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50234380(CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203853(CHEMBL221130 | N-{4-[1-(azetidine-1-carbonyl)-pipe...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50234380(CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi:  4nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203849(CHEMBL221904 | N-{4-[1-(2-amino-acetyl)-piperidin-...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203850(2-methyl-N-{4-[1-(piperidine-1-carbonyl)-piperidin...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203882(2-methyl-N-{4-[1-(4-methyl-piperazine-1-carbonyl)-...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203837(CHEMBL218503 | N-(4-cyclohexylsulfamoyl-naphthalen...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078161(CHEMBL3417702)
Affinity DataKi:  4.90nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203866(4-(4-o-tolylcarbamoyl-naphthalene-1-sulfonylamino)...)
Affinity DataKi:  5.21nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203878(CHEMBL218036 | N-{4-[1-(2-hydroxy-acetyl)-piperidi...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi:  6nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203875(2-methyl-N-[4-({[1-(morpholin-4-ylcarbonyl)piperid...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203910(CHEMBL221977 | N-(4-{[(1-acetylpiperidin-4-yl)amin...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203925(CHEMBL374979 | N-[4-(1-cyclopropanecarbonyl-piperi...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078163(CHEMBL3417704)
Affinity DataKi:  7.90nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078162(CHEMBL3417703)
Affinity DataKi:  8.80nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  9nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203921(CHEMBL219433 | N-[4-(1-cyclopentanecarbonyl-piperi...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203917(4-(4-cyclohexylcarbamoyl-naphthalene-1-sulfonylami...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi: <10nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203911(CHEMBL220703 | N-{4-[1-(3-amino-propionyl)-piperid...)
Affinity DataKi:  11.3nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078164(CHEMBL3417705)
Affinity DataKi:  12nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078158(CHEMBL3417699)
Affinity DataKi:  12nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203865(4-(4-benzoylamino-naphthalene-1-sulfonylamino)-pip...)
Affinity DataKi:  15.2nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203855(CHEMBL221961 | N-{4-[1-(2-methoxy-acetyl)-piperidi...)
Affinity DataKi:  15.8nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1486 total ) | Next | Last >>
Jump to: