Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
Affinity DataIC50: >63nMpH: 7.5Assay Description:Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair