TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 395nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 670nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 880nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.00E+3nM ΔG°: -33.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.00E+3nM ΔG°: -33.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)
Curated by ChEMBL
The Medicines Company (Leipzig)
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair