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Found 594 with Last Name = 'kudolo' and Initial = 'm'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50583520(CHEMBL5094006)
Affinity DataKi:  0.830nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused MPS1 (1 to 857 residues) using histone H3 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50313107(4-chloro-N-cyclopropyl-3-(1-(2,6-difluorophenyl)-1...)
Affinity DataKi:  1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50314780(CHEMBL1091199 | N-Cyclopropyl-3-(1-(2,4-difluoroph...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50418613(CHEMBL1232887)
Affinity DataKi:  9nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)
Affinity DataKi:  10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50263093(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopr...)
Affinity DataKi:  12nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50583520(CHEMBL5094006)
Affinity DataKi:  14.2nMAssay Description:Covalent inhibition of human full length N-terminal GST-fused MPS1 (1 to 857 residues) assessed as inhibition constant by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM25980(BMCL18324 Compound 3 | CHEMBL270164 | N-(3-cyanoph...)
Affinity DataKi:  240nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM25981(BMCL18324 Compound 17 | CHEMBL273158 | D3RKN_78 | ...)
Affinity DataKi:  480nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM245474(US9428503, 1)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604534(CHEMBL5191923 | US20230348462, Example 50)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604528(CHEMBL5183158 | US20230348462, Example 27)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604529(CHEMBL5181829 | US20230348462, Example 28)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50509054(CHEMBL1232751)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604533(CHEMBL5170132 | US20230348462, Example 49)
Affinity DataIC50:  0.920nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604502(CHEMBL5203201 | US20230348462, Example 7)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM258444(US9512130, 2)
Affinity DataIC50: <1nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused MPS1 (1 to 857 residues) using histone H3 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM532292(JGS79C | N-(2,6-diethylphenyl)-2-[2-methoxy-4-(4-m...)
Affinity DataIC50: <1nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused MPS1 (1 to 857 residues) using histone H3 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM258444(US9512130, 2)
Affinity DataIC50: <1nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604505(CHEMBL5171246 | US20230348462, Example 11)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604506(CHEMBL5179355 | US20230348462, Example 21)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604507(CHEMBL5204408 | US20230348462, Example 19)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604508(CHEMBL5204162 | US20230348462, Example 17)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604535(CHEMBL5198342 | US20230348462, Example 51)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM245474(US9428503, 1)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604504(CHEMBL5184135 | US20230348462, Example 10)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604528(CHEMBL5183158 | US20230348462, Example 27)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604534(CHEMBL5191923 | US20230348462, Example 50)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50509055(CHEMBL4575052)
Affinity DataIC50:  1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604513(CHEMBL5191914)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604533(CHEMBL5170132 | US20230348462, Example 49)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604512(CHEMBL5207887)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604511(CHEMBL5199423 | US20230348462, Example 16)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50494296(CHEMBL3086685)
Affinity DataIC50:  1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604510(CHEMBL5209108 | US20230348462, Example 15)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604529(CHEMBL5181829 | US20230348462, Example 28)
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50348310(CHEMBL1800911 | US8772288, 1)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604513(CHEMBL5191914)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50313107(4-chloro-N-cyclopropyl-3-(1-(2,6-difluorophenyl)-1...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604505(CHEMBL5171246 | US20230348462, Example 11)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604521(CHEMBL5195854 | US20230348462, Example 13)
Affinity DataIC50:  2nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50331622(5-amino-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50604503(CHEMBL5201821 | US20230348462, Example 8)
Affinity DataIC50:  2nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM20657(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-m...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50524536(CHEMBL4452170)
Affinity DataIC50:  3nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50331625(5-amino-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50503009(CHEMBL4526183)
Affinity DataIC50:  3nMAssay Description:Inhibition of GSK3beta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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