BDBM50253154 CHEMBL492265::N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-phthalazinyl)benzamide::N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide

SMILES Cc1ccccc1-c1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1

InChI Key InChIKey=GQXMJOSCBRZMKE-UHFFFAOYSA-N

Data  1 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50253154   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  5.52E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  6.63E+3nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed