TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -54.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -54.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -53.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -52.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I](R)-1-(3-iodophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1Hbenzo[e][1,4]diazepin-3-yl)urea from human CCK2 receptor expresse...More data for this Ligand-Target Pair