Affinity DataKi: 5.50E+3nMAssay Description:Competitive inhibition of recombinant rat DNA polymerase beta using poly(dA)/oligo(dT)18 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.85E+3nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
Affinity DataKi: 1.16E+4nMAssay Description:Noncompetitive inhibition of recombinant rat DNA polymerase beta using dTTP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+4nMAssay Description:Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Tokyo University Of Science
Curated by ChEMBL
Tokyo University Of Science
Curated by ChEMBL
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA templ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substr...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Kyoto Prefectural University
Curated by ChEMBL
Kyoto Prefectural University
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of His-tagged human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA templ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substr...More data for this Ligand-Target Pair
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Kyoto Prefectural University
Curated by ChEMBL
Kyoto Prefectural University
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of His-tagged human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of rat DNA polymerase beta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair