TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 1.79E+5nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]LTD4 binding on guinea-pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Leukotriene D4 induced contraction of guinea-pig trachea was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]-LTD4 binding on guinea-pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [3H]-LTD4 binding on guinea-pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [3H]-LTD4 binding on guinea-pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of [3H]-LTD4 binding on guinea-pig lung membranesMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair