BindingDB PrimarySearch

Found 84 with Last Name = 'lendvai' and Initial = 'b'

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

IC50: 1.80E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR stably expressed in HEK293 cells assessed as inhibition of acethylcholine-evoked currents by whole-cel...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

PC cid PC sid

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572670(CHEMBL4872371)

IC50: 4.60E+3nMAssay Description:Inhibition of human ERG channel expressed in CHO cells measured after 7 to 10 mins at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572638(CHEMBL4873077)

IC50: 7.50E+3nMAssay Description:Inhibition of human ERG channel expressed in CHO cells measured after 7 to 10 mins at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50250187(4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrr...)

EC50: 600nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563055(CHEMBL4744652)

EC50: 400nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50250186(4-(3-Acetyl-5-(4-chlorophenyl)-2-methyl-1H-pyrrol-...)

EC50: 1.90E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50250146(CHEMBL522299 | Ethyl 5-(4-Chlorophenyl)-2-methyl-1...)

EC50: 1.40E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563056(CHEMBL4796582)

EC50: 1.70E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563057(CHEMBL4753949)

EC50: 1.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563058(CHEMBL4750788)

EC50: 1.30E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563059(CHEMBL4756274)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563060(CHEMBL4763628)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563061(CHEMBL4788788)

EC50: 3.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563062(CHEMBL4740661)

EC50: 2.30E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563063(CHEMBL4779926)

EC50: 700nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563064(CHEMBL4798588)

EC50: 1.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563065(CHEMBL4799108)

EC50: 2.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563066(CHEMBL4746562)

EC50: 3.50E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563067(CHEMBL4743406)

EC50: 300nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563068(CHEMBL4751279)

EC50: 1.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563069(CHEMBL4792581)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563070(CHEMBL4748327)

EC50: 3.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563071(CHEMBL4788544)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563072(CHEMBL4781954)

EC50: 900nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563073(CHEMBL4750716)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563074(CHEMBL4780177)

EC50: 2.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563075(CHEMBL4791013)

EC50: 7.40E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563076(CHEMBL4783972)

EC50: 2.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563077(CHEMBL4785311)

EC50: 500nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563078(CHEMBL4761954)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563079(CHEMBL4793773)

EC50: 9.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563080(CHEMBL4744432)

EC50: 2.50E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563081(CHEMBL4752316)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563082(CHEMBL4761575)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563083(CHEMBL4740207)

EC50: 2.60E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563084(CHEMBL4745516)

EC50: 5.80E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563085(CHEMBL4792222)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563086(CHEMBL4759542)

EC50: 5.90E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563054(CHEMBL4745686)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563087(CHEMBL4786198)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563088(CHEMBL4747602)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563089(CHEMBL4797167)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563090(CHEMBL4763653)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563077(CHEMBL4785311)

EC50: 6.10E+3nMAssay Description:Positive allosteric modulation of recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in choline-...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50563054(CHEMBL4745686)

EC50: 4.50E+3nMAssay Description:Positive allosteric modulation of recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in choline-...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572634(CHEMBL4864764)

EC50: 910nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572635(CHEMBL4855193)

EC50: 260nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572636(CHEMBL4846787)

EC50: 120nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572637(CHEMBL4875161)

EC50: 3.00E+3nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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Neuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL

BDBM50572638(CHEMBL4873077)

EC50: 90nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

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