Affinity DataIC50: 0.430nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Antagonist activity at mouse GCGR expressed in CHO-K1 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity at mouse GCGR expressed in CHO-K1 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair