TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 7.44nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 7.99nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 12.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 15.1nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 23.2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 30.4nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 52nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 60.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Target6-phosphogluconate dehydrogenase, decarboxylating(Rattus norvegicus)
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of rat 6PGD assessed as inhibition constant by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 3.29E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 3.34E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 3.91E+3nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataKi: 4.65E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+5nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+5nMAssay Description:Competitive inhibition of adenylate kinase II in rat liver with respect to ATPMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+6nMAssay Description:Competitive inhibition of adenylate kinase III in rat liver with respect to ATPMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 4.70E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase III, activity expressed as Inhibition constant; Non competitive inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 5.90E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 6.80E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 7.30E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 7.30E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human MPS1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair