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Found 233 with Last Name = 'maeda' and Initial = 'm'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  7.44nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262557((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  7.99nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50244419((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Affinity DataKi:  15.1nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262557((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  23.2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  27nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  30.4nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261726((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261791((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50244419((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Affinity DataKi:  60.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Rattus norvegicus)
Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50590158(CHEMBL5174714)
Affinity DataKi:  100nMAssay Description:Inhibition of rat 6PGD assessed as inhibition constant by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261726((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261791((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262499((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50245093((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.29E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261727((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.34E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261727((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50245093((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262556((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262499((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.91E+3nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262556((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  4.65E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367068(CHEMBL3350524 | CHEMBL609795)
Affinity DataKi:  3.00E+5nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP:AMP phosphotransferase AK3, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027422(1N-{4-[9-(3,4-dihydroxy-5-hydroxymethyltetrahydro-...)
Affinity DataKi:  9.00E+5nMAssay Description:Competitive inhibition of adenylate kinase II in rat liver with respect to ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027422(1N-{4-[9-(3,4-dihydroxy-5-hydroxymethyltetrahydro-...)
Affinity DataKi:  1.10E+6nMAssay Description:Competitive inhibition of adenylate kinase III in rat liver with respect to ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367067(CHEMBL3350514 | CHEMBL612174)
Affinity DataKi:  1.60E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367066(CHEMBL3350509 | CHEMBL610373)
Affinity DataKi:  1.80E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367073(CHEMBL3350528 | CHEMBL609819)
Affinity DataKi:  1.90E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP:AMP phosphotransferase AK3, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367067(CHEMBL3350514 | CHEMBL612174)
Affinity DataKi:  2.10E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP:AMP phosphotransferase AK3, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367066(CHEMBL3350509 | CHEMBL610373)
Affinity DataKi:  2.20E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP:AMP phosphotransferase AK3, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367073(CHEMBL3350528 | CHEMBL609819)
Affinity DataKi:  2.40E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367071(CHEMBL607736)
Affinity DataKi:  4.70E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 4, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50010316(CHEMBL3251364)
Affinity DataKi:  4.80E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase III, activity expressed as Inhibition constant; Non competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP:AMP phosphotransferase AK3, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367075(CHEMBL3350513 | CHEMBL611859)
Affinity DataKi:  5.90E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP:AMP phosphotransferase AK3, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50010316(CHEMBL3251364)
Affinity DataKi:  6.20E+6nMAssay Description:Ability to inhibit rat adenylate kinase III, activity expressed as Inhibition constant; Competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367065(CHEMBL608643)
Affinity DataKi:  6.70E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367072(CHEMBL3350534 | CHEMBL610134)
Affinity DataKi:  6.80E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367070(CHEMBL609238)
Affinity DataKi:  7.30E+6nMAssay Description:Ability to inhibit Escherichia coli adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase 2, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367069(CHEMBL3350522 | CHEMBL609792)
Affinity DataKi:  7.30E+6nMAssay Description:Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072905(CHEMBL3410078)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072911(CHEMBL3410084)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072900(CHEMBL3410073)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50386816(CHEMBL2047943)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human MPS1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072900(CHEMBL3410073)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072905(CHEMBL3410078)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072911(CHEMBL3410084)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50433907(CHEMBL2380582)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072910(CHEMBL3410083)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072902(CHEMBL3410075)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50433906(CHEMBL2380583)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50072904(CHEMBL3410077)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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