Compile Data Set for Download or QSAR
maximum 50k data
Found 377 with Last Name = 'mcelvain' and Initial = 'm'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22209(1,2,4-oxadiazole based compound, 26 | 1-[(4-{5-[4-...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22203(1,2,4-oxadiazole based compound, 13 | 1-({4-[3-(4-...)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50158345(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3...)
Affinity DataIC50: >10nMAssay Description:Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22203(1,2,4-oxadiazole based compound, 13 | 1-({4-[3-(4-...)
Affinity DataIC50: >10nMAssay Description:Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22201(1,3,4-oxadiazole based compound, 9 | 1-({4-[5-(4-t...)
Affinity DataIC50: >10nMAssay Description:Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22209(1,2,4-oxadiazole based compound, 26 | 1-[(4-{5-[4-...)
Affinity DataIC50:  12nMAssay Description:Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50158345(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3...)
Affinity DataIC50:  37nMAssay Description:Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22201(1,3,4-oxadiazole based compound, 9 | 1-({4-[5-(4-t...)
Affinity DataIC50:  100nMAssay Description:Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50361891(CHEMBL1938952)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336946(1-((4-(5-(2-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-f...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335462(1-(4-(5-benzylbenzofuran-2-yl)-3-fluorobenzyl)azet...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human ERG by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50361891(CHEMBL1938952)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50361891(CHEMBL1938952)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  44nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21693(1-(2-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21694(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  6.39E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21695(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  5.10E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21696(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  1.02E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21697(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]pi...)
Affinity DataEC50:  690nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21698(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  830nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21699(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  1.52E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21700(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  2.71E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21701(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]py...)
Affinity DataEC50:  130nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21702(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Affinity DataEC50:  34nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21703(2-ethyl-1-[(3S)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Affinity DataEC50:  3.50E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21704(2-ethyl-1-[(3R)-1-[(5-fluoro-1H-indol-2-yl)carbony...)
Affinity DataEC50:  1.49E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21705(1-[(3R)-1-[(5-chloro-1H-indol-2-yl)carbonyl]pyrrol...)
Affinity DataEC50:  1.41E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21706(1-[(3R)-1-[(5-bromo-1H-indol-2-yl)carbonyl]pyrroli...)
Affinity DataEC50:  810nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21707(2-ethyl-1-[(3R)-1-{[5-(trifluoromethoxy)-1H-indol-...)
Affinity DataEC50:  1.22E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21708(2-ethyl-1-[(3R)-1-[(5-ethyl-1H-indol-2-yl)carbonyl...)
Affinity DataEC50:  270nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataEC50:  1.87E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186938(1-(3-tert-butyl-2-methyl-5-oxo-1-phenyl-2,5-dihydr...)
Affinity DataEC50:  83nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186939(1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1...)
Affinity DataEC50:  250nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186940(1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyra...)
Affinity DataEC50:  1.23E+4nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186942(1-(3-fluoro-4-methylphenyl)-3-(3-isopropyl-2-methy...)
Affinity DataEC50:  81nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186941(1-(4-cyanophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2...)
Affinity DataEC50:  3.70E+3nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186943(1-(4-bromophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2...)
Affinity DataEC50:  90nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186944(1-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methy...)
Affinity DataEC50:  5.13E+3nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21693(1-(2-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186945(1-(3-ethyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-...)
Affinity DataEC50:  310nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186950(1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyra...)
Affinity DataEC50:  4.85E+3nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186947(1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyra...)
Affinity DataEC50:  770nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186949(1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyra...)
Affinity DataEC50:  1.26E+3nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186948(1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyra...)
Affinity DataEC50:  2.73E+3nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186951(1-(3-chlorophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186953(1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,...)
Affinity DataEC50:  44nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186954(1-(4-chlorophenyl)-3-(3-ethyl-2-methyl-5-oxo-1-phe...)
Affinity DataEC50:  140nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50186956(1-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2...)
Affinity DataEC50:  150nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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