TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.00000600nMAssay Description:Displacement of [3H]GW0385 from HIV1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.0000150nMAssay Description:Displacement of [3H]GW0385 from HIV1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration of the compound against Monoamine oxidase B (MAO-B)More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against hog liverMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Triglutamyl homologue inhibition activity against AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) from L cellMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration of the compound against Monoamine oxidase A (MAO-A)More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against L cellMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration of the compound against lysyl oxidaseMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition activity against AICAR formyltransferase from hog liverMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.74E+5nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair