Compile Data Set for Download or QSAR
maximum 50k data
Found 139 with Last Name = 'messere' and Initial = 'a'
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM24498(3-(3-fluoro-4-{[2-(1-methyl-1H-imidazol-4-yl)thien...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-cyclopamine from human wild-type SMO receptor expressed in HEK293T cell membranes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-cyclopamine from human wild-type SMO receptor expressed in HEK293T cell membranes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250705(CHEMBL4078698)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027084(Melatonan)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027084(Melatonan)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241617(CHEMBL4068667)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241630(CHEMBL4065471)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250733(CHEMBL4064373)
Affinity DataIC50:  6nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250704(CHEMBL4089168)
Affinity DataIC50:  6nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027084(Melatonan)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603802(CHEMBL5187368)
Affinity DataIC50:  9nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603804(CHEMBL5206336)
Affinity DataIC50:  9.10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50:  9.10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241618(CHEMBL4064911)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241623(CHEMBL4102803)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027084(Melatonan)
Affinity DataIC50:  9.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241627(CHEMBL4105199)
Affinity DataIC50:  10nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241621(CHEMBL4095042)
Affinity DataIC50:  11nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241629(CHEMBL4100348)
Affinity DataIC50:  14nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603800(CHEMBL5205283)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241626(CHEMBL4080951)
Affinity DataIC50:  19nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250704(CHEMBL4089168)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250710(CHEMBL4061034)
Affinity DataIC50:  22nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241628(CHEMBL4084848)
Affinity DataIC50:  23nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241626(CHEMBL4080951)
Affinity DataIC50:  23nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603802(CHEMBL5187368)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50:  32nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241627(CHEMBL4105199)
Affinity DataIC50:  35nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  40nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241622(CHEMBL4074577)
Affinity DataIC50:  43nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603805(CHEMBL5172938)
Affinity DataIC50:  44nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603805(CHEMBL5172938)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603805(CHEMBL5172938)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241620(CHEMBL4073512)
Affinity DataIC50:  50nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  53nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241618(CHEMBL4064911)
Affinity DataIC50:  56nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603800(CHEMBL5205283)
Affinity DataIC50:  57nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603800(CHEMBL5205283)
Affinity DataIC50:  64nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241621(CHEMBL4095042)
Affinity DataIC50:  65nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50603800(CHEMBL5205283)
Affinity DataIC50:  69nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250721(CHEMBL4093767)
Affinity DataIC50:  70nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 139 total ) | Next | Last >>
Jump to: