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Found 199 with Last Name = 'mueller' and Initial = 'l'
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172757(CHEMBL3808801)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi:  1.40nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50098595(CHEMBL3594314)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human Tissue factor/factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192462((S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxy...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192463(2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid | ...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172726(CHEMBL3809352)
Affinity DataKi:  4nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172727(CHEMBL3808853)
Affinity DataKi:  6nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  8nMAssay Description:Inhibition of human Tissue factor/factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192465(2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-methoxyacet...)
Affinity DataKi:  9nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192463(2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid | ...)
Affinity DataKi:  16nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189415(US9174974, Comparator 4)
Affinity DataKi:  25nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi:  25nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172789(CHEMBL3809344)
Affinity DataKi:  31nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192462((S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxy...)
Affinity DataKi:  33nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  35nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172757(CHEMBL3808801)
Affinity DataKi:  36nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172727(CHEMBL3808853)
Affinity DataKi:  46nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192465(2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-methoxyacet...)
Affinity DataKi:  50nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50498202(CHEMBL3416136)
Affinity DataKi:  130nMAssay Description:Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189415(US9174974, Comparator 4)
Affinity DataKi:  140nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172788(CHEMBL3809993)
Affinity DataKi:  154nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi:  400nMAssay Description:Inhibition of human Tissue factor/factor 7aMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  510nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  610nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172788(CHEMBL3809993)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172726(CHEMBL3809352)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192464(1-(2,3-bis(2-chlorobenzyloxy)phenyl)ethane-1,2-dio...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192464(1-(2,3-bis(2-chlorobenzyloxy)phenyl)ethane-1,2-dio...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172727(CHEMBL3808853)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172727(CHEMBL3808853)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189415(US9174974, Comparator 4)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172789(CHEMBL3809344)
Affinity DataKi:  4.51E+3nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189415(US9174974, Comparator 4)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172728(CHEMBL3809472)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189415(US9174974, Comparator 4)
Affinity DataKi: >6.20E+3nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172726(CHEMBL3809352)
Affinity DataKi: >6.20E+3nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172726(CHEMBL3809352)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172726(CHEMBL3809352)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189415(US9174974, Comparator 4)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172788(CHEMBL3809993)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172757(CHEMBL3808801)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172789(CHEMBL3809344)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172727(CHEMBL3808853)
Affinity DataKi:  1.08E+4nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172726(CHEMBL3809352)
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172788(CHEMBL3809993)
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172789(CHEMBL3809344)
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172757(CHEMBL3808801)
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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