Affinity DataKi: 0.00250nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:In vitro inhibition of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nM Koff: 2.51E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonist activity against PGE2 activated EP1 receptor assessed as ability to inhibit intracellular calcium mobilisation by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO-K1 cells assessed as inhibition of PGE2-mediated intracellular calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Antagonist activity against human EP1 receptor expressed in CHOK1 cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nM ΔG°: -52.5kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair