Found 3944 with Last Name = 'nelson' and Initial = 'd' 
Affinity DataKi: 0.0200nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 0.130nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 1A receptor by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Antagonistic activity measured for 5-hydroxytryptamine 2A receptor using [3H]-MDL- 100,907 as radioligand in rat cortical homogenates.More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.247nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor by Panlabs assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity at 5-HT reuptake site labeled with [3H]-paroxetineMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding ability of compound at cloned human 5-hydroxytryptamine 2C receptor using [125 I]DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Agonistic activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nM ΔG°: -55.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Binding affinity at 5-HT reuptake site labeled with [3H]-paroxetineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity at 5-HT reuptake site labeled with [3H]-paroxetineMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity at human adrenergic beta2 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 0.440nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Agonistic activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Binding ability of compound at cloned human 5-hydroxytryptamine 2A receptor using [125 I]DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.515nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Binding affinity at human adrenergic beta1 receptorMore data for this Ligand-Target Pair
