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Found 750 with Last Name = 'orjales' and Initial = 'a'
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Faes

Curated by ChEMBL
LigandPNGBDBM29525(3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034281(Bicyclo[2.2.1]heptane-2-carboxylic acid {2-[4-(2-m...)
Affinity DataKi:  0.120nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034308(Bicyclo[2.2.1]heptane-2-carboxylic acid {4-[4-(2-m...)
Affinity DataKi:  0.230nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034292(CHEMBL25654 | Octahydro-pentalene-2-carboxylic aci...)
Affinity DataKi:  0.240nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034300(Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid {2-[4-(...)
Affinity DataKi:  0.270nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471508(CHEMBL63025)
Affinity DataKi:  0.316nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471510(CHEMBL294083)
Affinity DataKi:  0.316nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471501(CHEMBL62692)
Affinity DataKi:  0.316nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034303(Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid {4-[4-(...)
Affinity DataKi:  0.380nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471511(CHEMBL294109)
Affinity DataKi:  0.398nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50056404(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 3 receptor in rat enthorinal cortex using [3H]-LY 278584 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50103072(1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole | CHEM...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034302(CHEMBL23877 | Octahydro-pentalene-2-carboxylic aci...)
Affinity DataKi:  0.630nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.631nMAssay Description:Binding affinity was evaluated in vitro by displacement of [3H]ketanserin from 5-hydroxytryptamine 2A receptor on rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50103072(1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole | CHEM...)
Affinity DataKi:  0.631nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.631nMAssay Description:In vitro by displacement of [3H]raclopride from Dopamine receptor D2 on rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034296(1-Methyl-1H-pyrrole-2-carboxylic acid {4-[4-(2-met...)
Affinity DataKi:  0.740nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50005536(42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136145(4-[(4-Fluoro-phenyl)-(4-methoxy-phenoxy)-methyl]-p...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136200(4-[(4-Fluoro-phenoxy)-(4-fluoro-phenyl)-methyl]-pi...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136144(4-[(3-Fluoro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  1nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471500(CHEMBL59689)
Affinity DataKi:  1nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Faes

Curated by ChEMBL
LigandPNGBDBM85778(CAS_135938-17-9 | SB203186)
Affinity DataKi:  1nMAssay Description:In vitro by displacement of [3H]GR-113808 from 5-hydroxytryptamine 4 receptor on guinea pig striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136154(4-[(4-Fluoro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.18nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034288(1-Methyl-1H-pyrrole-2-carboxylic acid {2-[4-(2-met...)
Affinity DataKi:  1.19nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus mambranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  1.26nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.30nMAssay Description:In vitro by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor on rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136135(3-(Phenyl-piperidin-4-yl-methoxy)-benzonitrile | C...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136135(3-(Phenyl-piperidin-4-yl-methoxy)-benzonitrile | C...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136135(3-(Phenyl-piperidin-4-yl-methoxy)-benzonitrile | C...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034309(3-Methyl-thiophene-2-carboxylic acid {4-[4-(2-meth...)
Affinity DataKi:  1.53nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471504(CHEMBL294522)
Affinity DataKi:  1.60nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  1.60nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50471503(CHEMBL60102)
Affinity DataKi:  1.60nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034286(CHEMBL23904 | Cyclopentanecarboxylic acid {4-[4-(2...)
Affinity DataKi:  1.88nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136144(4-[(3-Fluoro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136132(4-[(3-Fluoro-5-methoxy-phenoxy)-phenyl-methyl]-pip...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136144(4-[(3-Fluoro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136131(4-[(4-Bromo-phenoxy)-phenyl-methyl]-piperidine | C...)
Affinity DataKi:  2nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi:  2nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50000483((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Affinity DataKi:  2nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136169(3-Fluoro-5-(phenyl-piperidin-4-yl-methoxy)-phenol ...)
Affinity DataKi:  2nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034282(CHEMBL282012 | Thiophene-3-carboxylic acid {4-[4-(...)
Affinity DataKi:  2.20nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034304(5-Methyl-thiophene-2-carboxylic acid {2-[4-(2-meth...)
Affinity DataKi:  2.29nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136157(4-(Phenoxy-phenyl-methyl)-piperidine | CHEMBL44718...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50034284(CHEMBL23449 | Thiophene-2-carboxylic acid {4-[4-(2...)
Affinity DataKi:  2.34nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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