Affinity DataKi: 1.23nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 2.75nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 18.6nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 243nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 247nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 311nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 353nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 692nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 905nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 1.74E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 1.88E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.11E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.16E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.62E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 3.31E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 4.03E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.97E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 5.40E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 5.80E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.46E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.66E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.03E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >8.00E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 3.70E+4nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged HGPRTMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human HDAC3 expressed in baculovirus infected insect cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 2nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info