Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP2 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human recombinant full-length PARP1 after 4 mins by [32P]NAD+ incorporation assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mouse recombinant PARP2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of PARP1 (unknown origin) by NAD+ based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PARP2 (unknown origin) by biotinylated NAD+-based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant full-length PARP1 after 4 mins by [32P]NAD+ incorporation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PARP1 by ELISAMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 49.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 53.2nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 56.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 61.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant PARP2 by ELISAMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 72.4nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 81.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 82.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 94.9nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of PARP1 (unknown origin) by colorimetric analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 97.4nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 99.1nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 133nMAssay Description:Inhibition of human recombinant TNKS1 by chemiluminescence assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University
Curated by ChEMBL
Affiliated To Sardar Patel University
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair