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Found 804 with Last Name = 'perez-medrano' and Initial = 'a'
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220746(CHEMBL292189)
Affinity DataKi:  0.0398nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220747(CHEMBL56863)
Affinity DataKi:  0.0631nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM139889(US8895592, 19)
Affinity DataKi:  0.150nMAssay Description:The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220750(CHEMBL55695)
Affinity DataKi:  0.158nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50160161(5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-pheny...)
Affinity DataKi:  0.251nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220788(CHEMBL417954)
Affinity DataKi:  0.251nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133287(US8846730, 40)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM133313(US8846730, 79)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133276(US8846730, 23)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133307(US8846730, 72)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135877(US8859596, 164)
Affinity DataKi:  0.300nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220744(CHEMBL55290)
Affinity DataKi:  0.316nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135855(US8859596, 141)
Affinity DataKi:  0.320nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135905(US8859596, 193)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM133287(US8846730, 40)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135909(US8859596, 198)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9807(US8846730, 50)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133315(US8846730, 81)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133313(US8846730, 79)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133308(US8846730, 73)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133275(US8846730, 22)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM133316(US8846730, 83)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM133276(US8846730, 23)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135905(US8859596, 193)
Affinity DataKi:  0.5nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220785(CHEMBL293149)
Affinity DataKi:  0.501nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135882(US8859596, 169)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135875(US8859596, 162)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135882(US8859596, 169)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135857(US8859596, 144)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9651(US8846730, 4)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM9651(US8846730, 4)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135904(US8859596, 192)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM9652(US8846730, 5)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135908(US8859596, 197)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135904(US8859596, 192)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135860(US8859596, 147)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135911(US8859596, 200)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM139889(US8895592, 19)
Affinity DataKi:  0.730nMAssay Description:The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM139900(US8895592, 30)
Affinity DataKi:  0.75nMAssay Description:The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM139906(US8895592, 37)
Affinity DataKi:  0.770nMAssay Description:The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220786(CHEMBL55629)
Affinity DataKi:  0.794nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220782(CHEMBL53675)
Affinity DataKi:  0.794nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9842(US8846730, 65 | US8846730, 76)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM135903(US8859596, 191)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135878(US8859596, 165)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135857(US8859596, 144)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM139902(US8895592, 32)
Affinity DataKi:  0.820nMAssay Description:The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9812(US8846730, 69)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135903(US8859596, 191)
Affinity DataKi:  0.900nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135900(US8859596, 188)
Affinity DataKi:  0.900nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
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