BindingDB PrimarySearch

Found 68 with Last Name = 'pethani' and Initial = 'jp'

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538416(CHEMBL4644835 | US11236045, Example 25)

IC50: 5.30nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538393(CHEMBL4647321 | US11236045, Example 1)

IC50: 6.80nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50155926(CHEMBL3183703)

IC50: 8nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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3D Structure (crystal)

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50155926(CHEMBL3183703)

IC50: 8nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538418(CHEMBL4641961 | US11236045, Example 54)

IC50: 12nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538405(CHEMBL4642066)

IC50: 15nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538407(CHEMBL4647621 | US11236045, Example 22)

IC50: 21nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538421(CHEMBL4649141 | US11236045, Example 30)

IC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547438(CHEMBL4752523)

IC50: 24nMAssay Description:Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of MSUMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547438(CHEMBL4752523)

IC50: 26nMAssay Description:Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericinMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547438(CHEMBL4752523)

IC50: 33nMAssay Description:Inhibition of NLRP3 (unknown origin) assessed as inhibition of IL-18 production by cell based assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538417(CHEMBL4643205 | US11236045, Example 55)

IC50: 34nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538406(CHEMBL4640151)

IC50: 35nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547438(CHEMBL4752523)

IC50: 35nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538420(CHEMBL4636825 | US11236045, Example 56)

IC50: 36nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547440(CHEMBL4758640)

IC50: 70nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547444(CHEMBL4759516)

IC50: 76nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547452(CHEMBL4791679)

IC50: 79nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547450(CHEMBL4745667)

IC50: 93nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547441(CHEMBL4756798)

IC50: 96nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538419(CHEMBL4646271)

IC50: 110nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Details Article PubMed

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547446(CHEMBL4756693)

IC50: 126nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547448(CHEMBL4742825)

IC50: 142nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547442(CHEMBL4778322)

IC50: 164nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547439(CHEMBL4792478)

IC50: 208nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547451(CHEMBL4778164)

IC50: 243nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547455(CHEMBL4751187)

IC50: 294nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547449(CHEMBL4753623)

IC50: 306nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547453(CHEMBL4758006)

IC50: 344nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547447(CHEMBL4795321)

IC50: 369nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538394(CHEMBL4640644)

IC50: >1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538395(CHEMBL4634472)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538396(CHEMBL4633580)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538397(CHEMBL4633769)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538398(CHEMBL4640804)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538399(CHEMBL4643011)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538400(CHEMBL4643208)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538401(CHEMBL4649621)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538402(CHEMBL4641660)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538403(CHEMBL4649881)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538404(CHEMBL4636808)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538408(CHEMBL4634682)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538409(CHEMBL4644865)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538410(CHEMBL4649429)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538411(CHEMBL4646037)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538412(CHEMBL4643062)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538413(CHEMBL4637610)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538414(CHEMBL4644503)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50538415(CHEMBL4635816)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid

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NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL

BDBM50547443(CHEMBL4744515)

IC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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