Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 26.1nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 34.5nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 51.5nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 53.8nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 58.2nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 154nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 173nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 411nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 455nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 526nMAssay Description:Displacement of [3H]WIN-35,428 from DAT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 646nMAssay Description:Displacement of [3H]citalopram from rat brain SERTMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 716nMAssay Description:Displacement of [3H]WIN-35428 from rat brain DATMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 1.46E+3nMAssay Description:Displacement of [3H]WIN-35428 from rat brain DATMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [3H]WIN-35,428 from DAT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Displacement of [3H]WIN-35,428 from DAT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Glasgow
Curated by ChEMBL
University Of Glasgow
Curated by ChEMBL
Affinity DataKi: 2.79E+3nMAssay Description:Displacement of [3H]citalopram from rat brain SERTMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PARP1 in human G7 cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PARP1 in human T98G cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of PARP1 in human G7 cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PARP1 in human T98G cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair