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Found 120 with Last Name = 'pons' and Initial = 'm'
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKi:  0.680nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKi:  0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371120(CHEMBL242173)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371127(CHEMBL244681)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371125(CHEMBL244088)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371131(CHEMBL390874)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371118(CHEMBL244693)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371123(CHEMBL244090)
Affinity DataKi:  2.40E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM38435(9-ethyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazole-6-ca...)
Affinity DataKi:  6.10E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371126(CHEMBL438508)
Affinity DataKi:  8.80E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371130(CHEMBL390873)
Affinity DataKi:  9.10E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371116(CHEMBL242148)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371117(CHEMBL242146)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371119(CHEMBL244696)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371121(CHEMBL440951)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371122(CHEMBL242363)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371124(CHEMBL244694)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371128(CHEMBL390401)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)

Curated by ChEMBL
LigandPNGBDBM50371129(CHEMBL244328)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556958(CHEMBL4744528)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556953(CHEMBL4748114)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556954(CHEMBL4782921)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50:  3nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471264(CHEMBL1627893)
Affinity DataIC50:  3nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471259(CHEMBL1627458)
Affinity DataIC50:  4nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556951(CHEMBL4788434)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556956(CHEMBL4741162)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556950(CHEMBL4743210)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556957(CHEMBL4794769)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471260(CHEMBL1628165)
Affinity DataIC50:  6nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471266(CHEMBL303196)
Affinity DataIC50:  7nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556958(CHEMBL4744528)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556955(CHEMBL4782267)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataIC50:  31nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556954(CHEMBL4782921)
Affinity DataIC50:  36nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556950(CHEMBL4743210)
Affinity DataIC50:  52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556953(CHEMBL4748114)
Affinity DataIC50:  52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556957(CHEMBL4794769)
Affinity DataIC50:  53nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556951(CHEMBL4788434)
Affinity DataIC50:  70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556956(CHEMBL4741162)
Affinity DataIC50:  78nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471588(CHEMBL1237293)
Affinity DataIC50:  150nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50:  181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471604(CHEMBL273663)
Affinity DataIC50:  200nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556955(CHEMBL4782267)
Affinity DataIC50:  290nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  300nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471262(CHEMBL1628147)
Affinity DataIC50:  320nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471587(CHEMBL13289)
Affinity DataIC50:  500nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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