Affinity DataKi: 0.680nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...More data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 2.40E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 6.10E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 8.80E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 9.10E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair