TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Glenmark Research Center
Curated by ChEMBL
Glenmark Research Center
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Glenmark Research Center
Curated by ChEMBL
Glenmark Research Center
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 157nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 3.79E+3nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Glenmark Research Center
Curated by ChEMBL
Glenmark Research Center
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Glenmark Research Center
Curated by ChEMBL
Glenmark Research Center
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 7.62E+3nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute Of Chemical Technology
Curated by ChEMBL
Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Glenmark Research Center
Curated by ChEMBL
Glenmark Research Center
Curated by ChEMBL
Affinity DataKi: 5.10E+4nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Glenmark Research Center
Curated by ChEMBL
Glenmark Research Center
Curated by ChEMBL
Affinity DataKi: 2.02E+5nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.25nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.81nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.43nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.67nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.94nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.47nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 11.3nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 11.6nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 12.7nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 13.1nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Rallis India
Curated by ChEMBL
Rallis India
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 16.3nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 16.7nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Rallis India
Curated by ChEMBL
Rallis India
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 17.6nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 18.1nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 18.1nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Rallis India
Curated by ChEMBL
Rallis India
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Rallis India
Curated by ChEMBL
Rallis India
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Rallis India
Curated by ChEMBL
Rallis India
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 19.4nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 20.5nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Rallis India
Curated by ChEMBL
Rallis India
Curated by ChEMBL
Affinity DataIC50: 20.6nMAssay Description:Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 20.6nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 22.2nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair