Found 98 with Last Name = 'prather' and Initial = 'pl' TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.370nM ΔG°: -53.8kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
Affinity DataKi: 0.395nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 9nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]CP 55940 from CB1 receptor in mouse whole brain membrane homogenates after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 9.80nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 9.80nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 10.9nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.9nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
Affinity DataKi: 12.9nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 14.1nM ΔG°: -44.8kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 15nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 15.4nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]CP-55940 from CB2 receptor (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
Affinity DataKi: 24.2nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 26.5nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]CP 55940 from CB1 receptor in mouse whole brain membrane homogenates after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 37.3nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cells incubated for 90 mins by liquid scintillation spectrophotometry relative ...More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]CP 55940 from CB1 receptor in mouse whole brain membrane homogenates after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
