Compile Data Set for Download or QSAR
maximum 50k data
Found 1211 with Last Name = 'rae' and Initial = 'a'
TargetSerine protease hepsin(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  0.270nMAssay Description:Inhibition of recombinant human hepsin preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553757(CHEMBL4746471)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50326722((Z)-3-(4-(N-(4-chlorophenyl)-N-(2-oxo-2-(2-(2-oxoi...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512103(CHEMBL4464524)
Affinity DataKi:  0.670nMAssay Description:Inhibition of recombinant human hepsin preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50326722((Z)-3-(4-(N-(4-chlorophenyl)-N-(2-oxo-2-(2-(2-oxoi...)
Affinity DataKi:  0.670nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410616(CHEMBL2113185)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM403740(6-Chloro-7-((3-(cyclopropylmethyl)-7-methyl-3H-imi...)
Affinity DataKi:  0.900nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410618(CHEMBL2113181)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553762(CHEMBL4758608)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410625(CHEMBL2113201)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant human matriptase preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410634(CHEMBL2113189)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553761(CHEMBL4756857)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553754(CHEMBL4746482)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553763(CHEMBL4785208)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553764(CHEMBL4749423)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410622(CHEMBL2113203)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512103(CHEMBL4464524)
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant human matriptase preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410634(CHEMBL2113189)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410619(CHEMBL2113208)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512103(CHEMBL4464524)
Affinity DataKi:  3.70nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410640(CHEMBL2113198)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553760(CHEMBL4757188)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553753(CHEMBL4799496)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM400239(7-((1-(2-Cyclopropylethyl)-5-fluoro-1H-benzo[d]imi...)
Affinity DataKi:  4.10nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410623(CHEMBL2113179)
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410625(CHEMBL2113201)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM400243(6-((3-(Cyclopropylmethyl)-7-methyl-3H-imidazo[4,5-...)
Affinity DataKi:  6.40nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM400238(7-((1-((3,3-Difluorocyclobutyl)methyl)-5-fluoro-1H...)
Affinity DataKi:  6.70nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM400240(7-((1-(Cyclopropylmethyl)-5-fluoro-4-methyl-1H-ben...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553759(CHEMBL4760677)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410621(CHEMBL2113177)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410635(CHEMBL2113211)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  7.20nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410616(CHEMBL2113185)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410638(CHEMBL2113207)
Affinity DataKi:  8.70nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553765(CHEMBL4754539)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410630(CHEMBL2113209)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553747(CHEMBL4753738)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553749(CHEMBL4761336)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM400240(7-((1-(Cyclopropylmethyl)-5-fluoro-4-methyl-1H-ben...)
Affinity DataKi:  11.8nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410619(CHEMBL2113208)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553758(CHEMBL4800521)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553756(CHEMBL4785991)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178153(4-ethoxy-N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178186(CHEMBL372122 | N-(4-chlorophenyl)-4-ethoxy-N-{2-[(...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50410622(CHEMBL2113203)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM400242(N-(6-(1H-Imidazol-1-yl)pyridin-3-yl)-3-(cyclopropy...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50553745(CHEMBL4785872)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1211 total ) | Next | Last >>
Jump to: