Found 1190 with Last Name = 'rotili' and Initial = 'd' TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of PRC2 catalytic core EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of G9a (unknown origin) assessed as reduction in substrate methylation using histone H3 and SAM as substrate measured after 15 to 60 mins ...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
