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Found 51 with Last Name = 'rozanov' and Initial = 'dv'
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8443(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataKi:  32nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8435(3-[(5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylide...)
Affinity DataKi:  800nM IC50:  1.70E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8442(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  265nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8441(2-[(5Z)-5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl...)
Affinity DataIC50:  298nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8439(2-[(5Z)-5-{[5-(4-chloro-2-nitrophenyl)furan-2-yl]m...)
Affinity DataIC50:  500nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8444(2-[(5Z)-4-oxo-5-[(5-phenylthiophen-2-yl)methyliden...)
Affinity DataIC50:  740nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8438(2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  850nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8437(2-[(5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylide...)
Affinity DataIC50:  900nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8458(5-[(5-phenylthiophen-2-yl)methylidene]-2-sulfanyli...)
Affinity DataIC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8456(5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-...)
Affinity DataIC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8447(2-[(5Z)-5-[(5-{[(5Z)-3-(carboxymethyl)-4-oxo-2-sul...)
Affinity DataIC50:  1.60E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8457(5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylidene}-...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8434(4-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  2.30E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8459(2-[(5Z)-4-oxo-2-sulfanylidene-5-{[5-(thiophen-2-yl...)
Affinity DataIC50:  2.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8433(2-chloro-4-(5-{[(5Z)-4-oxo-3-(prop-2-en-1-yl)-2-su...)
Affinity DataIC50:  2.70E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8432(3-[(5Z)-5-{[5-(4-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  2.70E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8431(4-(5-{[(5Z)-4-oxo-2-sulfanylidene-3-[3-(trifluorom...)
Affinity DataIC50:  2.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8464(5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl]methyli...)
Affinity DataIC50:  3.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8440(2-[(5Z)-5-{[5-(2-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  3.10E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8430(2-[(5Z)-5-{[5-(3-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  3.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8446(2-[(5Z)-5-{[5-(4-chlorophenyl)thiophen-2-yl]methyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8460(5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}-2-su...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8451(2-[(5Z)-5-{[5-(4-bromophenyl)-1,3-thiazol-2-yl]met...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8429(4-(5-{[(5Z)-3-(4-nitrophenyl)-4-oxo-2-sulfanyliden...)
Affinity DataIC50:  4.80E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8450(2-[(5Z)-5-{[5-(3,4-dimethoxyphenyl)-1,3-thiazol-2-...)
Affinity DataIC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8428(2-[(5Z)-5-{[5-(4-iodophenyl)furan-2-yl]methylidene...)
Affinity DataIC50:  5.50E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8463(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  5.60E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8452(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  5.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8427(4-(5-{[(5Z)-3-benzyl-4-oxo-2-sulfanylidene-1,3-thi...)
Affinity DataIC50:  6.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8426((5Z)-5-{[5-(4-bromo-3-chlorophenyl)furan-2-yl]meth...)
Affinity DataIC50:  7.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8425((5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylid...)
Affinity DataIC50:  7.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8424(2-[(5Z)-4-oxo-5-{[5-(4-sulfamoylphenyl)furan-2-yl]...)
Affinity DataIC50:  9.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8423(2-chloro-4-(5-{[(5Z)-4-oxo-3-(pyridin-3-ylmethyl)-...)
Affinity DataIC50:  9.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8449(2-[(5Z)-5-{[5-(4-chlorophenyl)-1,3-thiazol-2-yl]me...)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8422((5Z)-3-(furan-2-ylmethyl)-5-{[5-(4-nitrophenyl)fur...)
Affinity DataIC50:  1.26E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8421(3-[(5Z)-5-{[5-(2-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  1.28E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8461(2-[(5Z)-4-oxo-5-[(5-phenylfuran-2-yl)methylidene]-...)
Affinity DataIC50:  1.66E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8420(4-[(5Z)-5-{[5-(3-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8462(2-[(5Z)-5-{[5-(4-fluorophenyl)-1,3-thiazol-2-yl]me...)
Affinity DataIC50:  2.24E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8419((5Z)-5-{[5-(2-nitrophenyl)furan-2-yl]methylidene}-...)
Affinity DataIC50:  3.19E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8418((5Z)-3-(furan-2-ylmethyl)-5-{[5-(3-nitrophenyl)fur...)
Affinity DataIC50:  3.63E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8417((5Z)-3-(4-hydroxyphenyl)-5-{[5-(4-nitrophenyl)fura...)
Affinity DataIC50:  3.77E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8416((5Z)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}...)
Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8448(2-[(5Z)-4-oxo-2-sulfanylidene-5-(1,3-thiazol-2-ylm...)
Affinity DataIC50:  7.24E+4nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8445(2-[(5Z)-4-oxo-2-sulfanylidene-5-(thiophen-2-ylmeth...)
Affinity DataIC50:  7.94E+4nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8455(Creatinine acetic acid analogue 20 | [(5E)-5-{[5-(...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8454((5E)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]fur...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8436(2-[(5Z)-5-(furan-2-ylmethylidene)-4-oxo-2-sulfanyl...)
Affinity DataIC50:  1.40E+5nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8415((5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}...)
Affinity DataIC50:  1.50E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8453((5E)-5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}...)
Affinity DataIC50:  2.00E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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