TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Binding affinity of the compound to human Tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity of the compound to human Tachykinin receptor 1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125 I]-Tyr8 SP from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Antagonism of NK1 receptor in rat liver microsomes.More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]-labeled SP from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:compounds were evaluated for inhibitory activity against human Tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]-labeled SP from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Antagonism of NK1 receptor in rat liver microsomes.More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Antagonism of NK1 receptor in rat liver microsomes.More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Antagonism of NK1 receptor in rat liver microsomes.More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in CHO cells was measured by its ability to displace [125I]- Tyr-8 substance P.More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Antagonism of NK1 receptor in rat liver microsomes.More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Displacement of [125 I]-Tyr8 SP from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Binding affinity at human tachykinin receptor 1 by measuring its ability to displace [125I]-labeled substance P from the cloned receptor expressed in...More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Binding affinity against wild type human Tachykinin receptor 1 expressed in CHO cells was measured by its ability to displace [125I]- Tyr-8 substance...More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair