Affinity DataIC50: 0.190nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR (Arg498 to 514Pro residues) binding to recombinant FLAG-tagged BCL6 BTB (5 to 129 residues) (unknown or...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase obtained from humanMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase obtained from porcineMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Displacement of [3H]-AD-5061 from human GST-tagged PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human SMS2 expressed in HEK293T cells using C2-ceramide as substrate preincubated for 60 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Compound was evaluated for the inhibition of thymidylate synthase obtained from humanMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of biotinylated C-terminal BCOR (unknown origin) binding to wild-type BCL6 BTB domain (5 to 129 amino acid residues) (unknown origin) by E...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of human SMS2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair