TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human TSPOMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat heart membrane homogenateMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human CA7 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human CA7 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.670nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human CA7 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human CA7 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of rat TSPOMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.860nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.990nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat kidneyMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.19nMAssay Description:Displacement of [3H]PK11195 from TSPO in human HEK293 mitochondrial fractionMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human CA2 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat kidneyMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat heart membrane homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Stanford University School Of Medicine
Curated by ChEMBL
Stanford University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair