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Found 53 with Last Name = 'stroth' and Initial = 'n'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50274835(CHEMBL511857 | trans-1-(4-(3-methoxyphenyl)cyclohe...)
Affinity DataKi:  0.0280nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50107249(1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...)
Affinity DataKi:  0.160nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50033843(1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-yliden...)
Affinity DataKi:  0.310nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50107234(1-[3-(5-Methoxy-naphthalen-1-yl)-propyl]-4-pyridin...)
Affinity DataKi:  0.380nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50033852(1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataKi:  0.480nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253281(CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to rat cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395193(CHEMBL2164330)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395191(CHEMBL494675)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395187(CHEMBL2164334)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395189(CHEMBL2164332)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395198(CHEMBL2164329)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395203(CHEMBL2164338)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395194(CHEMBL2164343)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395199(CHEMBL2164328)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395196(CHEMBL2164339)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395195(CHEMBL2164341)
Affinity DataKi:  14.9nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253281(CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395193(CHEMBL2164330)
Affinity DataKi:  17.4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395200(CHEMBL2164344)
Affinity DataKi:  18.4nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395202(CHEMBL2164340)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50107245(1-[4-(3-Methoxy-phenyl)-butyl]-4-pyridin-2-yl-pipe...)
Affinity DataKi:  23nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395190(CHEMBL2164331)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395196(CHEMBL2164339)
Affinity DataKi:  31.4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395188(CHEMBL2164333)
Affinity DataKi:  63.2nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395190(CHEMBL2164331)
Affinity DataKi:  72.1nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395195(CHEMBL2164341)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395205(CHEMBL2164335)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395201(CHEMBL2164342)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395191(CHEMBL494675)
Affinity DataKi:  99nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395188(CHEMBL2164333)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395194(CHEMBL2164343)
Affinity DataKi:  149nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50001862((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Affinity DataKi:  243nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Affinity DataKi:  352nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataKi:  476nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395204(CHEMBL2164337)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataIC50:  438nMAssay Description:Antagonist activity at human 5HT7A receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395191(CHEMBL494675)
Affinity DataIC50:  531nMAssay Description:Antagonist activity at human 5HT7A receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50107249(1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50274835(CHEMBL511857 | trans-1-(4-(3-methoxyphenyl)cyclohe...)
Affinity DataEC50:  0.324nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50033843(1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-yliden...)
Affinity DataEC50:  3.39E+3nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50107249(1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Karolinska Institute And Karolinska University Hospital

Curated by ChEMBL
LigandPNGBDBM50033852(1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataEC50:  0.776nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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