Compile Data Set for Download or QSAR
maximum 50k data
Found 1037 with Last Name = 'tam' and Initial = 'b'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257637(1-(4-aminopyridin-2-yl)-4-phenyl-N-(quinolin-2-yl)...)
Affinity DataKi:  17nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257723(2-(3-phenyl-3H-spiro[isobenzofuran-1,4'-piperidine...)
Affinity DataKi:  18nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50375654(CHEMBL99203 | US11633415, Compound 5-iodotubercidi...)
Affinity DataKi:  30nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257639((1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4-yl)(3...)
Affinity DataKi:  35nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50368712(CHEMBL608051)
Affinity DataKi:  40nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400788(CHEMBL2203612)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257684(CHEMBL495346 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Affinity DataKi:  82nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50368710(CHEMBL607761)
Affinity DataKi:  150nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50368709(CHEMBL607766)
Affinity DataKi:  160nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257638(CHEMBL493743 | ethyl 4-(1-(4-aminopyridin-2-yl)-4-...)
Affinity DataKi:  169nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50368707(CHEMBL612205)
Affinity DataKi:  170nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257683(1-(4-aminopyridin-2-yl)-N-(4-methoxybenzyl)-4-phen...)
Affinity DataKi:  201nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50368708(CHEMBL611890)
Affinity DataKi:  300nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257685(CHEMBL492330 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Affinity DataKi:  343nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257833(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-benzyl...)
Affinity DataKi:  518nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257686(CHEMBL522317 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Affinity DataKi:  548nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257834(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-(cyclo...)
Affinity DataKi:  746nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257831(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-(4-met...)
Affinity DataKi:  865nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257832(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-phenyl...)
Affinity DataKi:  903nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257781(2-(3-(3-methoxyphenyl)-3-methylazetidin-1-yl)pyrid...)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257780((S)-1'-(4-aminopyridin-2-yl)-N,N-dimethyl-2,3-dihy...)
Affinity DataKi:  4.71E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257782(CHEMBL493515 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi:  5.03E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50368706(CHEMBL607762)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human placental adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257784(CHEMBL493517 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi:  9.69E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257830(CHEMBL493781 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257783(CHEMBL493516 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257719((S)-N-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257722((S)-1'-(4-aminopyridin-2-yl)-N,N-diethyl-3H-spiro[...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Pacific University Oregon

Curated by ChEMBL
LigandPNGBDBM50088436(BS-749 | CHEBI:76987 | Metacetamol)
Affinity DataKi:  9.50E+6nMAssay Description:Inhibition of human CYP2E1 assessed as chlorzoxazone 6-hydroxylase activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276291(CHEMBL472464 | N-benzyl-N-(1'-(2,6-dimethylbenzoyl...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291559(CHEMBL268473 | {2-Benzo[1,3]dioxol-5-yl-1-[(S)-2-b...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189399((S)-N-(3-(4-(2-(4-fluorophenyl)acetamido)piperidin...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291555(CHEMBL276690 | {2-Benzo[1,3]dioxol-4-yl-1-[(S)-2-b...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291558(CHEMBL276872 | {1-[(S)-2-Biphenyl-4-yl-1-(1H-tetra...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50064106(CGS-26303 | CHEMBL290698 | {[(R)-2-Biphenyl-4-yl-1...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50064106(CGS-26303 | CHEMBL290698 | {[(R)-2-Biphenyl-4-yl-1...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  1nMAssay Description:Inhibition of CYP2C9 using a fluorescent probe 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276260((R)-N-benzyl-N-(1-(1-(2,6-dimethylbenzoyl)piperidi...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276259(CHEMBL481068 | exo-N-benzyl-N-((R)-1-(8-(2,6-dimet...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50064106(CGS-26303 | CHEMBL290698 | {[(R)-2-Biphenyl-4-yl-1...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of rat neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400791(CHEMBL2203619)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291557(CHEMBL268761 | {1-[(S)-2-Biphenyl-4-yl-1-(1H-tetra...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50379503(CHEMBL2012415)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400795(CHEMBL2203615)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189401(CHEMBL214818 | N-((S)-3-(3-(2-methyl-1H-benzo[d]im...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384165(CHEMBL2029908)
Affinity DataIC50:  2nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384169(CHEMBL2029912)
Affinity DataIC50:  2nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384168(CHEMBL2029911)
Affinity DataIC50:  2nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384167(CHEMBL2029910)
Affinity DataIC50:  2nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1037 total ) | Next | Last >>
Jump to: