Compile Data Set for Download or QSAR
maximum 50k data
Found 101 with Last Name = 'tanuma' and Initial = 's'
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataKi:  20nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataKi:  3.30E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Kao

Curated by ChEMBL
LigandPNGBDBM50354041(CHEMBL1829584)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of neutral endopeptidase in human fibroblasts homogenates using glutaryl-Ala-Ala-Phe-4-methoxy-2-naphtylamide as substrate after 1 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Kao

Curated by ChEMBL
LigandPNGBDBM50354042(CHEMBL1829585)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of neutral endopeptidase in human fibroblasts homogenates using glutaryl-Ala-Ala-Phe-4-methoxy-2-naphtylamide as substrate after 1 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Kao

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of neutral endopeptidase in human fibroblasts homogenates using glutaryl-Ala-Ala-Phe-4-methoxy-2-naphtylamide as substrate after 1 hrs by ...More data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
Kao

Curated by ChEMBL
LigandPNGBDBM50354040(CHEMBL1829583)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of neutral endopeptidase in human fibroblasts homogenates using glutaryl-Ala-Ala-Phe-4-methoxy-2-naphtylamide as substrate after 1 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50:  70nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50:  70nMAssay Description:Inhibition of mushroom tyrosinase after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50157547(2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  70nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataIC50:  90nMAssay Description:Inhibition of mushroom tyrosinase after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataIC50:  90nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Kao

Curated by ChEMBL
LigandPNGBDBM50354044(CHEMBL1829587)
Affinity DataIC50:  420nMAssay Description:Inhibition of neutral endopeptidase in human fibroblasts homogenates using glutaryl-Ala-Ala-Phe-4-methoxy-2-naphtylamide as substrate after 1 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Kao

Curated by ChEMBL
LigandPNGBDBM50354043(CHEMBL1829586)
Affinity DataIC50:  430nMAssay Description:Inhibition of neutral endopeptidase in human fibroblasts homogenates using glutaryl-Ala-Ala-Phe-4-methoxy-2-naphtylamide as substrate after 1 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant human His-tagged glyoxalase 1 expressed in Escherichia coli BL21 assessed as formation of S-D-lactoylglutathione after 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50045936((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Affinity DataIC50:  760nMAssay Description:Inhibition of human N-terminal His6-tagged GLO1 expressed in baculovirus infected sf21 cells assessed as reduction in S-D-lactoylglutathione formatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50:  1.15E+3nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50326997(CHEMBL590878 | Delphinidin)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant glyoxalase 1 assessed as S-D-lactoylglutathione after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50355547(CHEMBL1910548)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged glyoxalase 1 expressed in Escherichia coli BL21 assessed as formation of S-D-lactoylglutathione after 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569128(CHEMBL4853249)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569120(CHEMBL4861582)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569133(CHEMBL4875229)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192743(3,4-Dihydroxybenzaldehyde | CHEBI:50205 | Protocat...)
Affinity DataIC50:  2.89E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569134(CHEMBL4863408)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569131(CHEMBL4852940)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease gamma(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acidsoluble DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569129(CHEMBL4851336)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569125(CHEMBL4871220)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569130(CHEMBL1303934)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50145829(4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50145829(4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569127(CHEMBL4877301)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569121(CHEMBL1162436)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM54054((E)-3-(1,3-benzoxazol-2-yl)-4-(4-methoxyphenyl)-3-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569132(CHEMBL4848220)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569124(CHEMBL4877073)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50195793(CHEMBL123234)
Affinity DataIC50:  6.97E+3nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50195793(CHEMBL123234)
Affinity DataIC50:  6.97E+3nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569123(CHEMBL4874418)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192745(CHEBI:75844 | CHEMBL3343985)
Affinity DataIC50:  8.40E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataIC50:  8.98E+3nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192746(CHEMBL3343986)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of tyrosinase in human HMV-2 melanoma cells after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50569126(CHEMBL4849720)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) assessed as inhibition of S-D-lactoylglutathione formation using MG and reduced glutathione as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50:  9.53E+3nMAssay Description:Inhibition of mushroom tyrosinase after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50:  9.53E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus systemMore data for this Ligand-Target Pair
TargetLactoylglutathione lyase(Homo sapiens (Human))
Tokyo University Of Science

Curated by ChEMBL
LigandPNGBDBM50241503(2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopy...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human recombinant glyoxalase 1 assessed as S-D-lactoylglutathione after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 101 total ) | Next | Last >>
Jump to: