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Found 39 with Last Name = 'tatum' and Initial = 'pr'
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399673(CHEMBL2178343)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399674(CHEMBL2178344)
Affinity DataIC50:  180nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  210nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  270nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399675(CHEMBL2178345)
Affinity DataIC50:  350nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  780nMAssay Description:Inhibition of HDAC2 by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399673(CHEMBL2178343)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399674(CHEMBL2178344)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant SIRT2 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50004135(CHEMBL3236132)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human recombinant SIRT2 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50004137(CHEMBL3236133)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human recombinant SIRT2 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399675(CHEMBL2178345)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC4 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399675(CHEMBL2178345)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of HDAC4 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399675(CHEMBL2178345)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of HDAC4 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399675(CHEMBL2178345)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of HDAC2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399674(CHEMBL2178344)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of HDAC2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of human recombinant SIRT3 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399673(CHEMBL2178343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50004135(CHEMBL3236132)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SIRT1 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399673(CHEMBL2178343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399674(CHEMBL2178344)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50004137(CHEMBL3236133)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SIRT1 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50004135(CHEMBL3236132)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SIRT3 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50004137(CHEMBL3236133)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SIRT3 using Fluor-de-Lys as substrate incubated for 60 mins prior to substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399673(CHEMBL2178343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC4 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC4 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50399674(CHEMBL2178344)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC4 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed