Compile Data Set for Download or QSAR
maximum 50k data
Found 34 with Last Name = 'terai' and Initial = 't'
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  0.282nMAssay Description:Adenosine A1 receptor binding using [3H]DPCPX in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataKi:  0.490nMAssay Description:Adenosine A1 receptor binding using [3H]DPCOX in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataKi:  0.490nMAssay Description:Adenosine A1 receptor binding using [3H]DPCPX in human cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079654(4-(6-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)py...)
Affinity DataKi:  6.60nMAssay Description:Adenosine A1 receptor using [3H]DPCOX in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  151nMAssay Description:Adenosine A2 receptor binding using [3H]CGS-21680 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079654(4-(6-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)py...)
Affinity DataKi:  1.20E+3nMAssay Description:Adenosine A2 receptor binding using [3H]CGS-21680 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataKi:  1.26E+3nMAssay Description:Adenosine A2 receptor binding using [3H]CGS-21680 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50287703((E)-1-[(S)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of adenosine induced negative inotropic activity against guinea-pig atria (Adenosine A1 receptor)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of adenosine induced negative inotropic activity against guinea-pig atria (Adenosine A1 receptor)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of [3H]-CHA binding against Adenosine A1 receptors of rat cortical membranes; Not testedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50287703((E)-1-[(S)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  17nMAssay Description:Inhibition of [3H]-CHA binding against Adenosine A1 receptors of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of ASK1 (unknown origin) by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Saitama University

Curated by ChEMBL
LigandPNGBDBM50573258(CHEMBL4869568)
Affinity DataIC50:  70nMAssay Description:Binding affinity to biotinylated human IL-17A assessed as inhibition of IL-17A interaction with 1L-17RA by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50287704((E)-1-(2-Ethyl-piperidin-1-yl)-3-(2-methyl-6-pheny...)
Affinity DataIC50:  91nMAssay Description:Inhibition of adenosine induced negative inotropic activity against guinea-pig atria (Adenosine A1 receptor) at 10 nMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM7491((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ASK1 (unknown origin) by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataIC50:  656nMAssay Description:Compound was evaluated for inhibition of adenosine induced relaxation against guinea-pig aorta (Adenosine A2 receptor).More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ASK1 (unknown origin) by fluorescence correlation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of [3H]NECA specific binding against Adenosine A2 receptors of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of adenosine induced negative inotropic activity against guinea-pig atria (Adenosine A1 receptor)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287703((E)-1-[(S)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  1.18E+3nMAssay Description:Compound was evaluated for inhibition of adenosine induced relaxation against guinea-pig aorta (Adenosine A2 receptor).More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM7491((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of ASK1 (unknown origin) by fluorescence correlation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of [3H]-CHA binding against Adenosine A1 receptors of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50287703((E)-1-[(S)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of [3H]NECA specific binding against Adenosine A2 receptors of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50243715(3-((1-methyl-1H-indol-3-yl)methylene)indolin-2-one...)
Affinity DataIC50:  8.27E+4nMAssay Description:Inhibition of ASK1 (unknown origin) by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50243715(3-((1-methyl-1H-indol-3-yl)methylene)indolin-2-one...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ASK1 (unknown origin) by fluorescence correlation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of adenosine induced relaxation against guinea-pig aorta (Adenosine A2 receptor).More data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of [3H]NECA specific binding against Adenosine A2 receptors of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-17A(Homo sapiens (Human))
Saitama University

Curated by ChEMBL
LigandPNGBDBM50573257(CHEMBL4878993)
Affinity DataKd:  13nMAssay Description:Binding affinity to human IL-17A assessed as dissociation constant in PBS-T measured after 60 mins by Biolayer interferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Saitama University

Curated by ChEMBL
LigandPNGBDBM50573258(CHEMBL4869568)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to biotinylated human IL-17A by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Saitama University

Curated by ChEMBL
LigandPNGBDBM50573256(CHEMBL4854787)
Affinity DataKd:  89nMAssay Description:Binding affinity to human IL-17A assessed as dissociation constant in PBS-T measured after 60 mins by Biolayer interferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Saitama University

Curated by ChEMBL
LigandPNGBDBM50573255(CHEMBL4858175)
Affinity DataKd:  12nMAssay Description:Binding affinity to human IL-17A assessed as dissociation constant in PBS-T measured after 60 mins by Biolayer interferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50243867(CHEMBL478889 | STS-PEG-TAMRA)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to ASK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataKd:  110nMAssay Description:Binding affinity to ASK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Saitama University

Curated by ChEMBL
LigandPNGBDBM50573254(CHEMBL4872876)
Affinity DataKd:  110nMAssay Description:Binding affinity to human IL-17A assessed as dissociation constant in PBS-T measured after 60 mins by Biolayer interferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed