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Found 16 with Last Name = 'thompson' and Initial = 'mj'
TargetFlap endonuclease 1 [1-336](Homo sapiens (Human))
University of Sheffield

LigandPNGBDBM197162(3-hydroxy-1-(4-methoxybenzyl)quinazoline-2,4(1H,3H...)
Affinity DataIC50:  16.9nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1 [1-336](Homo sapiens (Human))
University of Sheffield

LigandPNGBDBM197161(1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,...)
Affinity DataIC50:  30nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1 [1-336](Homo sapiens (Human))
University of Sheffield

LigandPNGBDBM50157840(1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-3-...)
Affinity DataIC50:  46.4nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500399(CHEMBL3746906)
Affinity DataIC50:  160nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500401(CHEMBL3746593)
Affinity DataIC50:  420nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500404(CHEMBL3747333)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500403(CHEMBL3746996)
Affinity DataIC50:  940nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500400(CHEMBL3747196)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500402(CHEMBL3747607)
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500403(CHEMBL3746996)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500399(CHEMBL3746906)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500404(CHEMBL3747333)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500402(CHEMBL3747607)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500401(CHEMBL3746593)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Sheffield

Curated by ChEMBL
LigandPNGBDBM50500400(CHEMBL3747196)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed