Compile Data Set for Download or QSAR
maximum 50k data
Found 53 with Last Name = 'thygesen' and Initial = 'mb'
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataKi:  0.0300nM ΔG°:  -55.8kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataKi:  0.0460nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.0830nM ΔG°:  -53.5kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.440nM ΔG°:  -49.6kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  0.550nM ΔG°:  -49.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  1.30nM ΔG°:  -47.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataKi:  1.30nM ΔG°:  -47.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataKi:  1.60nM ΔG°:  -46.7kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataKi:  3.80nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  0.0690nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataIC50:  1nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataIC50:  1.10nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataIC50:  1.90nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  3nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  4.5nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50:  13nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataIC50:  91nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50:  100nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50:  200nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataIC50:  540nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240819(CHEMBL4084119)
Affinity DataEC50:  0.0670nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50121394(CHEMBL3616711)
Affinity DataEC50:  0.0230nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50152769(CHEMBL410972 | GLP-1(7-36)-NH2 | GLP-17-(7-36) der...)
Affinity DataEC50:  0.0440nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240820(CHEMBL4073765)
Affinity DataEC50:  0.0680nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240821(CHEMBL4100575)
Affinity DataEC50:  0.221nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240822(CHEMBL4079706)
Affinity DataEC50:  0.547nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240823(CHEMBL4083273)
Affinity DataEC50:  0.118nMAssay Description:Binding affinity against dopamine receptor D2 by using [3H]spiperone as radioligand in caudate-putamen of monkeyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlbumin(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240510(CHEMBL898 | DIFLUNISAL)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to human serum albuminMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240824(CHEMBL4062410)
Affinity DataEC50:  0.148nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240825(CHEMBL4103967)
Affinity DataEC50:  0.522nMAssay Description:Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415088(CHEMBL577196)
Affinity DataEC50:  1.58nMAssay Description:Agonist activity at androgen receptor in human MDA-KB2 cells transfected with MMTV linked luciferase assessed as transcriptional activation by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415100(CHEMBL570413)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415099(CHEMBL569985)
Affinity DataEC50:  15.8nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415098(CHEMBL570898)
Affinity DataEC50:  15.8nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415097(CHEMBL570897)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415096(CHEMBL568814)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258791(4-(3-exo-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl)napht...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415095(CHEMBL568786)
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415094(CHEMBL578199)
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415093(CHEMBL570463)
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415092(CHEMBL570895)
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415091(CHEMBL576474)
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415090(CHEMBL576275)
Affinity DataEC50:  100nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlbumin(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human serum albuminMore data for this Ligand-Target Pair
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415088(CHEMBL577196)
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415087(CHEMBL570237)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50415086(ACP-105 | CHEMBL570435)
Affinity DataEC50:  1nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 53 total ) | Next | Last >>
Jump to: