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Found 74 with Last Name = 'topai' and Initial = 'a'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50026872(CHEMBL1233506 | SC-74020)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366175(CHEMBL1957606)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366175(CHEMBL1957606)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50475205(CHEMBL190899)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366203(CHEMBL1957601)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366175(CHEMBL1957606)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366175(CHEMBL1957606)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366205(CHEMBL1957603)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366203(CHEMBL1957601)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366205(CHEMBL1957603)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50:  16nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366175(CHEMBL1957606)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)
Affinity DataIC50:  34nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50088570((S)-2-(3-Benzoyl-phenyl)-propionic acid | (S)-2-(3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  53nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50475204(CHEMBL192943)
Affinity DataIC50:  80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  100nMAssay Description:Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50:  160nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  160nMAssay Description:Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366200(CHEMBL1957598)
Affinity DataIC50:  200nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366200(CHEMBL1957598)
Affinity DataIC50:  230nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  400nMAssay Description:Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  480nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  500nMAssay Description:Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366202(CHEMBL1957600)
Affinity DataIC50:  560nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  600nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366205(CHEMBL1957603)
Affinity DataIC50:  700nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366202(CHEMBL1957600)
Affinity DataIC50:  710nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366198(CHEMBL1957596)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366198(CHEMBL1957596)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366176(CHEMBL1957575)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366173(CHEMBL1957604)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366199(CHEMBL1957597)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366197(CHEMBL1957595)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366185(CHEMBL1957584)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366176(CHEMBL1957575)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366201(CHEMBL1957599)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366197(CHEMBL1957595)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366205(CHEMBL1957603)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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