Affinity DataKi: 1.83E+5nMAssay Description:Inhibitory constant against Glyoxalase IMore data for this Ligand-Target Pair
Affinity DataIC50: 11.5nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 27.7nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 43.6nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on TubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 445nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Displacement of [gamma-32P]-ATP from Epidermal growth factor receptor in A431 cell-free extractsMore data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferaseMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [gamma-32P]-ATP from Epidermal growth factor receptor in A431 cell-free extractsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Displacement of [gamma-32P]-ATP from Epidermal growth factor receptor in A431 cell-free extractsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Shinshu University
Curated by ChEMBL
Shinshu University
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in autophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Displacement of [gamma-32P]-ATP from Epidermal growth factor receptor in A431 cell-free extractsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMpH: 6.8 T: 2°CAssay Description:The IC50 values were obtained from a spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair