TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 5 (VLA-5)More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 5 (VLA-5)More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of His tagged Escherichia coli ATCC 25922 DNA gyrase A SD-LY mutant expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduc...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ERG at 37 degCMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of His tagged Escherichia coli ATCC 25922 DNA gyrase A SD-LY mutant expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduc...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6.14E+3nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by alpha4-beta7 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by alpha4-beta7 integrinMore data for this Ligand-Target Pair