Affinity DataKi: 0.180nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of purified human coagulation factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of thrombin (unknown origin) by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 186nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 187nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair