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Found 61 with Last Name = 'white' and Initial = 're'
LigandPNGBDBM50049201(2-Cyclopropyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-...)
Affinity DataKi:  2.90nMAssay Description:Receptor binding affinity determined from competitive binding assay using 1251 labelled [Sar1,Ile8] angiotensin II in rat adrenocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525013(CHEMBL4476440 | US11401286, Example 81)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524997(CHEMBL4570605 | US11401286, Example 58)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human His6-tagged PDE4D2 expressed in baculovirus infected Sf9 insect cells using cAMP as substrate preincubated for 5 to 1...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525005(CHEMBL4459298 | US11401286, Example 171)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524998(CHEMBL4564798 | US11401286, Example 62)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524991(CHEMBL4544243 | US11401286, Example 57)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525009(CHEMBL4437670 | US11401286, Example 191)
Affinity DataIC50:  57nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525003(CHEMBL4449185 | US11401286, Example 182)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198247(2-(3,4-dimethylphenyl)-3-(4-methoxyphenethyl)-2-me...)
Affinity DataIC50:  69nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198249(2-(3,4-dimethylphenyl)-3-(4-methoxybenzyloxy)thiaz...)
Affinity DataIC50:  95nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525000(CHEMBL4561428 | US11401286, Example 120)
Affinity DataIC50:  98nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525006(CHEMBL4434783 | US11401286, Example 80)
Affinity DataIC50:  105nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198255(2-(3,4-dichlorophenyl)-3-(4-methoxybenzyloxy)thiaz...)
Affinity DataIC50:  113nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524994(CHEMBL4541964 | US11401286, Example 142)
Affinity DataIC50:  127nMAssay Description:Inhibition of recombinant human His6-tagged PDE4D2 expressed in baculovirus infected Sf9 insect cells using cAMP as substrate preincubated for 5 to 1...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524995(CHEMBL4593524 | US11401286, Example 195)
Affinity DataIC50:  128nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525004(CHEMBL4553222 | US11401286, Example 3)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525008(CHEMBL4567525 | US11401286, Example 125)
Affinity DataIC50:  137nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099574(2-(3,4-Dimethyl-phenyl)-3-[2-(4-methoxy-phenyl)-et...)
Affinity DataIC50:  137nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198261(1-(2-(3,4-dimethylphenyl)thiazolidin-3-yl)-3-(4-me...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198260(1-(2-(3,4-dimethylphenyl)thiazolidin-3-yl)-2-pheno...)
Affinity DataIC50:  162nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525011(CHEMBL4569780 | US11401286, Example 119)
Affinity DataIC50:  166nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198254(2-(3,4-dimethylphenyl)-3-(2-methoxybenzyloxy)thiaz...)
Affinity DataIC50:  177nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198257(2-(3,4-dichlorophenyl)-3-(3-methoxybenzyloxy)thiaz...)
Affinity DataIC50:  179nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198256(2-(4-chlorophenyl)-3-(4-methoxybenzyloxy)thiazolid...)
Affinity DataIC50:  187nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198244(2-(3,4-dichlorophenyl)-3-(2-methoxybenzyloxy)thiaz...)
Affinity DataIC50:  204nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198258(3-(benzyloxy)-2-(3,4-dimethylphenyl)thiazolidin-4-...)
Affinity DataIC50:  207nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524996(CHEMBL4573171 | US11401286, Example 65)
Affinity DataIC50:  225nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50049408(CHEMBL3315270 | US11401286, Example 40)
Affinity DataIC50:  241nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198252(2-(3,4-dimethylphenyl)-3-(3-methoxybenzyloxy)thiaz...)
Affinity DataIC50:  269nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524999(CHEMBL4518460 | US11401286, Example 121)
Affinity DataIC50:  356nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198248(2-(4-chlorophenyl)-3-(3-methoxybenzyloxy)thiazolid...)
Affinity DataIC50:  380nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198246(3-(4-methoxyphenethyl)-2-methyl-2-p-tolylthiazolid...)
Affinity DataIC50:  390nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198259(3-(benzyloxy)-2-(3,4-dichlorophenyl)thiazolidin-4-...)
Affinity DataIC50:  463nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198251(3'-(4-methoxyphenethyl)-4-methyl-2,3-dihydrospiro[...)
Affinity DataIC50:  487nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198250(1-(2-(3,4-dimethylphenyl)thiazolidin-3-yl)-2-(4-me...)
Affinity DataIC50:  537nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525007(CHEMBL4440664 | US11401286, Example 6)
Affinity DataIC50:  562nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524993(CHEMBL4458210 | US11401286, Example 67)
Affinity DataIC50:  584nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50049409(CHEMBL3315269 | US11401286, Example 39)
Affinity DataIC50:  781nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198245(5-chloro-3'-(4-methoxyphenethyl)-2,3-dihydrospiro[...)
Affinity DataIC50:  812nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198253(3-(4-methoxybenzyloxy)-2-phenylthiazolidin-4-one |...)
Affinity DataIC50:  924nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525012(CHEMBL4472119 | US11401286, Example 181)
Affinity DataIC50:  953nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198243(3-(benzyloxy)-2-(4-chlorophenyl)thiazolidin-4-one ...)
Affinity DataIC50:  997nMAssay Description:Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50049418(CHEMBL3315275 | US11401286, Example 59)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524992(CHEMBL4455430 | US11401286, Example 102)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525010(CHEMBL4520584 | US11401286, Example 2)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524994(CHEMBL4541964 | US11401286, Example 142)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50524995(CHEMBL4593524 | US11401286, Example 195)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners

Curated by ChEMBL
LigandPNGBDBM50525002(CHEMBL4533457)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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