Found 381 with Last Name = 'winzeler' and Initial = 'e' TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Binding affinity to human 20S constitutive proteasome beta 5 subunit assessed as equilibrium constant using fluorogenic peptide Ac-WLA-AMC as substra...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKi: 375nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKi: 487nMAssay Description:Binding affinity to human 20S constitutive proteasome beta 2 subunit assessed as equilibrium constant using fluorogenic peptide Ac-WLR-AMC as substra...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKi: 3.74E+3nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKi: 3.92E+4nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presen...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presen...More data for this Ligand-Target Pair
3D Structure (crystal)TargetProteasome subunit beta type-9(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant full length human C-terminal His/FLAG tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human 20S constitutive proteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of C-terminal FLAG/His-tagged human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate me...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant full length human C-terminal His/FLAG tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant full length human C-terminal His/FLAG tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant full length human C-terminal His/FLAG tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human 20S constitutive proteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence...More data for this Ligand-Target Pair
