Affinity DataKi: 0.160nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.190nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.210nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.240nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.310nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.510nMAssay Description:Binding affinity to maltase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using maltose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.600nMAssay Description:Binding affinity to maltase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using maltose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.690nMAssay Description:Binding affinity to maltase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using maltose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.770nMAssay Description:Binding affinity to maltase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using maltose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.840nMAssay Description:Binding affinity to maltase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using maltose as substrate incubat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.90nMAssay Description:Binding affinity at endothelin receptor subtype AMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity at type 1 angiotensin 2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat prostatic vas deferens (Alpha-1A adrenergic receptor )More data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:Competitive inhibition of rat intestinal sucrase using sucrose as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Competitive inhibition of rat intestinal sucrase using sucrose as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 216nMAssay Description:Competitive inhibition of rat intestinal sucrase using sucrose as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of the cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
Affinity DataKi: 353nMAssay Description:Competitive inhibition of rat intestinal sucrase using sucrose as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Functional Histamine H1 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 785nMAssay Description:Competitive inhibition of rat intestinal sucrase using sucrose as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Functional Histamine H3 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Functional H2 receptor antagonistic activity in vitro assay on the isolated spontaneously beating guinea-pig right atriumMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat prostatic vas deferens (alpha1A receptor)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Antagonistic activity against (-)-phenylephrine-induced contraction of rat spleen (Alpha-1B adrenergic receptor )More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Functional H2 receptor antagonistic activity in vitro assay on the isolated spontaneously beating guinea-pig right atriumMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Functional Histamine H3 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Functional Histamine H1 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Functional H2 receptor antagonistic activity in vitro assay on the isolated spontaneously beating guinea-pig right atriumMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Functional H2 receptor antagonistic activity in vitro assay on the isolated spontaneously beating guinea-pig right atriumMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Functional Histamine H3 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Inhibition of FGFR3 (unknown origin) using TK as substrate incubated for 1 hr in presence of biotin/ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human BTK (382 to 659 residues) expressed in baculovirus infected Sf21 insect cells preincubated for 15 mins followed by ATP addition a...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Inhibition of FGFR2 (unknown origin) using TK as substrate incubated for 1 hr in presence of biotin/ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase overexpressed in HEK293F cells using EET as substrate assessed as formation of DHET incubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate asses...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of FGFR1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate asses...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair